As summer approaches, cases of Tick-borne diseases (TBDs) are on the rise. Lyme disease (LD) is the most common TBD and is generally cured with antibiotic treatment. Testing relies on detecting a patient’s immune response to infection. However, diagnosis of LD can be challenging. Optimal diagnostic accuracy of LD can be achieved by combining two separate antibody tests with consideration of a patient’s symptoms and tick exposure.
KOL Spotlight Interviews is a segment where we interview experts from various fields on their expertise and insights that help shape the diagnostic and pharmaceutical industries. This month, we had the pleasure of speaking to Dr. Balazs Halmos, Professor of Medicine, Chief, Thoracic/Head & Neck Oncology, Montefiore Medical Center/Albert Einstein College of Medicine. In this interview, Dr. Halmos shared his experience as an oncologist during the COVID-19 pandemic, particularly with hematological malignancies, or blood cancers.
What is celiac disease? Celiac disease (CD), also known as gluten-sensitive enteropathy, is prompted by an autoimmune…
Bartonellosis is an infectious disease caused by Bartonella species and is implicated in causing many emerging and re-emerging infections globally. While there are multiple species, the three most common Bartonella species (and the infections they cause) are: Bartonella henselae (Cat Scratch Disease), Bartonella quintana (Trench fever), and Bartonella bacilliformis (Oroya fever).
Autoimmune neurological disorders encompass disorders of nervous system caused by dysfunction of the immune system. Through this…
Food sensitivity Food sensitivity could be caused by increased permeability of the small intestine (as called leaky…
Dengue fever has no specific treatment, but supportive care can help manage the symptoms. Only one vaccine, Dengvaxia® from Sanofi, has been approved by the FDA to prevent severe disease. It is approved for children aged 9 to 16 who live in an endemic area and have previously been infected with DENV as confirmed by a laboratory serological assay.
In the autoimmune kidney disease Membranous Nephropathy (MN), the immune system launches an attack against the glomerulus of the kidney, which normally aids in filtering fluids and wastes. In 2009, autoantibodies against phospholipase A2 receptor (PLA2R) were discovered to be responsible for MN and have been shown to have a high diagnostic value.
Many families of patients with autoimmune encephalitis suffer in silence; without understanding the outcome of their family member’s diagnosis. However, two patient families, the “Egger’s and McDow’s” aimed to change this. Both families’ journeys with autoimmune encephalitis lead to the formation one of the world’s largest organizations to support patients and advance research in the diagnosis and treatment of autoimmune encephalitis. Listen and read about their empowering journey that led to the formation of “Autoimmune Encephalitis Alliance”.
Rheumatoid Arthritis (RA) is caused when the immune system sends antibodies to attack your joints, leading to joint destruction and disability. While there is no current cure for RA, treatment is possible. Treatment of RA is best done within 3 to 6 months after symptoms start, since permanent joint damage can occur within the first 2 years. This blog will discuss the common antibodies which are tested for in RA diagnosis, and highlight additional uses of antibody testing in RA.