What is celiac disease? Celiac disease (CD), also known as gluten-sensitive enteropathy, is prompted by an autoimmune…
Bartonellosis is an infectious disease caused by Bartonella species and is implicated in causing many emerging and re-emerging infections globally. While there are multiple species, the three most common Bartonella species (and the infections they cause) are: Bartonella henselae (Cat Scratch Disease), Bartonella quintana (Trench fever), and Bartonella bacilliformis (Oroya fever).
Autoimmune neurological disorders encompass disorders of nervous system caused by dysfunction of the immune system. Through this…
Food sensitivity Food sensitivity could be caused by increased permeability of the small intestine (as called leaky…
Dengue fever has no specific treatment, but supportive care can help manage the symptoms. Only one vaccine, Dengvaxia® from Sanofi, has been approved by the FDA to prevent severe disease. It is approved for children aged 9 to 16 who live in an endemic area and have previously been infected with DENV as confirmed by a laboratory serological assay.
In the autoimmune kidney disease Membranous Nephropathy (MN), the immune system launches an attack against the glomerulus of the kidney, which normally aids in filtering fluids and wastes. In 2009, autoantibodies against phospholipase A2 receptor (PLA2R) were discovered to be responsible for MN and have been shown to have a high diagnostic value.
Many families of patients with autoimmune encephalitis suffer in silence; without understanding the outcome of their family member’s diagnosis. However, two patient families, the “Egger’s and McDow’s” aimed to change this. Both families’ journeys with autoimmune encephalitis lead to the formation one of the world’s largest organizations to support patients and advance research in the diagnosis and treatment of autoimmune encephalitis. Listen and read about their empowering journey that led to the formation of “Autoimmune Encephalitis Alliance”.
Rheumatoid Arthritis (RA) is caused when the immune system sends antibodies to attack your joints, leading to joint destruction and disability. While there is no current cure for RA, treatment is possible. Treatment of RA is best done within 3 to 6 months after symptoms start, since permanent joint damage can occur within the first 2 years. This blog will discuss the common antibodies which are tested for in RA diagnosis, and highlight additional uses of antibody testing in RA.
The number of Powassan virus (POWV) reported cases is low compared to other tick-borne diseases such as Lyme disease. However, the prevalence of POWV infection is likely underestimated because testing capabilities are limited. There are no FDA-cleared assays and only a few commercially available assays. There is a need to increase the awareness of POWV infection to include this testing in clinical routine labs.
Allergy testing identifies common allergens including foods and inhalation that are often harmless but may cause allergies in some patients. There are two main allergy testing methods, skin-prick and blood tests, that can assess the presence of allergen-specific IgE antibodies. Combining an IgE-antibody blood test result with case history and a physical examination has clear clinical advantages when making a diagnosis.