Missed our webinar on bone turnover markers? Don’t sweat it! Discover how BTMs provide real-time insights into skeletal health, helping clinicians monitor osteoporosis treatment effectiveness in our on-demand webinar. Bone experts Dr. Paul Miller and Dr. Jennifer Kelly dive into the breadth of research behind BTMs’ efficacy in osteoporosis and why they believe all clinicians should be utilizing bone turnover markers in their clinical practice.
Euroimmun’ s EUROPattern and its advanced classifier are transforming laboratory workflows by enhancing accuracy, speed, and efficiency. By enabling rapid and reliable interpretation of immunofluorescence patterns, the system not only streamlines laboratory operations but also supports physicians in making quicker, more informed decisions.
The endocrine system is a powerful but often overlooked network of glands and hormones that orchestrates metabolism, growth, reproduction, and more. This post explores how it works, what happens when it goes awry, and how endocrine disorders are diagnosed and treated.
Discover the role of free testosterone, its impact on health, and why accurate testing is crucial for diagnosing androgen-related disorders in all genders.
We sat down with Dr. Dana Mitchell to hear her experience with autoimmune encephalitis, including her symptoms,…
Learn about Oropouche virus (OPOV) symptoms, diagnosis, and testing as cases surge across North America. Stay informed on Oropouche infection, detection, and prevention.
As dengue continues to pose a significant public health challenge globally, the importance of reliable diagnostic solutions cannot be overstated. Dengue testing is a critical tool in the fight against this disease, enabling healthcare providers to diagnose, treat, and manage dengue infections more effectively.
More than 100 biological drugs have been approved by the Food and Drug Administration (FDA) in the…
Growth disorders are one reason why patients are referred to endocrinologists. Pediatric endocrinologists diagnose growth hormone deficiency or excess and provide treatment options for children. Blood tests, such as IGF-I, aid the making of correct diagnosis.
Dermatomycosis refers to a fungal infection of the hair, skin, and nails which are caused by fungi called dermatophytes, in addition to molds and yeasts. In this blog, we summarize the key points of our recent review article on “The need for fast and accurate detection of dermatomycosis” including how newer molecular methods can help close the “diagnostic gap” observed with traditional fungal diagnostics and allow for a rapid detection of dermatomycosis with increased accuracy.
As summer approaches, cases of Tick-borne diseases (TBDs) are on the rise. Lyme disease (LD) is the most common TBD and is generally cured with antibiotic treatment. Testing relies on detecting a patient’s immune response to infection. However, diagnosis of LD can be challenging. Optimal diagnostic accuracy of LD can be achieved by combining two separate antibody tests with consideration of a patient’s symptoms and tick exposure.
KOL Spotlight Interviews is a segment where we interview experts from various fields on their expertise and insights that help shape the diagnostic and pharmaceutical industries. This month, we had the pleasure of speaking to Dr. Balazs Halmos, Professor of Medicine, Chief, Thoracic/Head & Neck Oncology, Montefiore Medical Center/Albert Einstein College of Medicine. In this interview, Dr. Halmos shared his experience as an oncologist during the COVID-19 pandemic, particularly with hematological malignancies, or blood cancers.
What is celiac disease? Celiac disease (CD), also known as gluten-sensitive enteropathy, is prompted by an autoimmune…
Bartonellosis is an infectious disease caused by Bartonella species and is implicated in causing many emerging and re-emerging infections globally. While there are multiple species, the three most common Bartonella species (and the infections they cause) are: Bartonella henselae (Cat Scratch Disease), Bartonella quintana (Trench fever), and Bartonella bacilliformis (Oroya fever).
Autoimmune neurological disorders encompass disorders of nervous system caused by dysfunction of the immune system. Through this…
Food sensitivity Food sensitivity could be caused by increased permeability of the small intestine (as called leaky…
Dengue fever has no specific treatment, but supportive care can help manage the symptoms. Only one vaccine, Dengvaxia® from Sanofi, has been approved by the FDA to prevent severe disease. It is approved for children aged 9 to 16 who live in an endemic area and have previously been infected with DENV as confirmed by a laboratory serological assay.
In the autoimmune kidney disease Membranous Nephropathy (MN), the immune system launches an attack against the glomerulus of the kidney, which normally aids in filtering fluids and wastes. In 2009, autoantibodies against phospholipase A2 receptor (PLA2R) were discovered to be responsible for MN and have been shown to have a high diagnostic value.
Many families of patients with autoimmune encephalitis suffer in silence; without understanding the outcome of their family member’s diagnosis. However, two patient families, the “Egger’s and McDow’s” aimed to change this. Both families’ journeys with autoimmune encephalitis lead to the formation one of the world’s largest organizations to support patients and advance research in the diagnosis and treatment of autoimmune encephalitis. Listen and read about their empowering journey that led to the formation of “Autoimmune Encephalitis Alliance”.
Rheumatoid Arthritis (RA) is caused when the immune system sends antibodies to attack your joints, leading to joint destruction and disability. While there is no current cure for RA, treatment is possible. Treatment of RA is best done within 3 to 6 months after symptoms start, since permanent joint damage can occur within the first 2 years. This blog will discuss the common antibodies which are tested for in RA diagnosis, and highlight additional uses of antibody testing in RA.
The number of Powassan virus (POWV) reported cases is low compared to other tick-borne diseases such as Lyme disease. However, the prevalence of POWV infection is likely underestimated because testing capabilities are limited. There are no FDA-cleared assays and only a few commercially available assays. There is a need to increase the awareness of POWV infection to include this testing in clinical routine labs.
Allergy testing identifies common allergens including foods and inhalation that are often harmless but may cause allergies in some patients. There are two main allergy testing methods, skin-prick and blood tests, that can assess the presence of allergen-specific IgE antibodies. Combining an IgE-antibody blood test result with case history and a physical examination has clear clinical advantages when making a diagnosis.
Autoimmune liver diseases (ALD) occur when the immune system turns against liver cells, leading to inflammation. Types of ALD include autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). The detection of specific disease-associated antibodies allows for a differential diagnosis of the culprit ALD, and helps to ensure proper patient treatment. Here we discuss the specific autoantibodies associated with either AIH, PBC, or PSC, as well as the techniques available for their detection.
As the Delta variant spreads across the world, many vaccinated individuals are worried about the possibility of a breakthrough infection. The term “breakthrough infection” refers to the development of a COVID-19 infection despite an individual being vaccinated against the virus. With many Americans still reluctant to vaccination, and with mask mandates lifted in most states, the highly contagious Delta virus has contributed to spikes in COVID-19 cases across the nation this summer ’21.
KOL Spotlight Interviews is a segment where we interview experts in various fields on their expertise and insights that continue to help shape the diagnostics and pharmaceutical industries. This month, we have the pleasure of welcoming Dr. Animesh Sinha, a renowned dermatologist from University at Buffalo. Below, we will learn more about diagnostic methods for autoimmune bullous dermatoses conditions.
Dermatophyte infections are difficult to diagnose clinically as they can resemble other skin disorders. Without proper diagnosis and treatment, dermatophyte infections can lead to permanent damage of the hair, skin, and nails. Molecular diagnostic testing of fungal infections allows for the accurate detection of dermatophytes that might be difficult to grow in culture, or in cases where a dermatophyte infection has already been treated, and allows for species-specific identification.
Meet Lisa Ann, a patient who was diagnosed with a rare autoimmune skin blistering disease after many misdiagnoses. She shares her story from the first symptoms and frustrations, testing and multiple doctor visits, and how she lives and manages this condition today. Check out this Patient Journey to hear from Lisa Ann and learn what diagnostic tests are available for these rare skin diseases.
Invasive Aspergillosis (IA) is an infection caused by Aspergillus. People with weakened immune systems or lung diseases are at a higher risk of developing IA. It is one of the most commonly under-detected diagnoses in ICU patients. Because symptoms are not specific, it is important to know which diagnostic tests can aid in early detection and management of IA.
Dr. Ruth Brignall completed a PhD in immunology and a post-doc in cancer biology. She joined Oxford Immunotec, first as a Medical Science Liaison (MSL) and more recently as a Global Medical Expert. Below, we will learn more about her experiences and insights in tuberculosis and SARS-CoV-2 diagnostics.
Less than a year after the World Health Organization (WHO) declared COVID-19 a global pandemic, the authorization of several novel COVID-19 vaccines has created hope for a healthier future. Recent studies have demonstrated that both humoral and cellular immunity play a role in protection from COVID-19. Additionally, the development of novel COVID-19 vaccines requires a look at the immune response in order to determine the effectiveness of the vaccine at preventing infection.
There is a need for continuous monitoring of therapeutic levels of TNF-α inhibitors to promote individualized treatment while affirming that patients receive the most accurate and cost-effective regimen available. With the MabTrack ELISA, clinicians can make effective adjustments based on semi-quantitative results and can facilitate simplified decision-making with their patients for improved long-term response.
SARS-CoV-2, commonly known as the coronavirus disease 2019 (COVID-19) poses an unprecedented public health crisis. While scientists and clinicians worldwide are still working to understand the virus, recent studies show possible onset of autoimmune diseases following COVID-19 infection.
The recent study conducted by De Meyer et al. demonstrated that EUROIMMUN ELISA and SIMOA (single molecule array) platform detected cerebral amyloidosis with equivalent accuracy through measuring the plasma Aβ42/Aβ40 ratio.
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